This volume discusses recent insights into the major components of the known canonical and non-canonical inflammasome complexes and mechanisms. It highlights their action, in particular in response to infection with important bacterial model pathogens and corresponding disease pathologies.
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The complementary actions of the innate and adaptive immune systems often provide effective host defense against microbial pathogens and harmful.
Mar 17, 2020 importantly, enteric bacterial pathogens can actively engage or evade inflammasome signalling systems.
Inflammasome signaling, some of them even challeng- ing the existing dogma. Bacterial infections: nlrp3-mediated caspase-1 activation regulates.
Nov 28, 2020 this initiates a signalling cascade, guiding the formation of the inflammasome and generation of inactive “pro” forms of pro-inflammatory.
The hin-200 family member, aim2, acts as a sensor for cytosolic bacterial, viral and host dsdna figure: inflammasome signaling - download the wallchart.
It is possible that other bacterial pamps, such as peptidoglycan, may provide a priming signal (signal 1) to upregulate inflammasome components, while.
Sep 25, 2020 monocytogenes–induced inflammasome activation, we next determined whether this signaling restricted bacterial infection.
May 16, 2017 please find our updated view of the inflammasome signalling the inflammasome: an anti-microbial machinery against bacterial infection.
From publication: bacterial recognition pathways that lead to inflammasome activation inflammasomes are multi-protein signaling platforms.
Animated film - noncanonical inflammasomes: signalling, pyroptosis and by a wide range of microbial, stress, and environmental stimuli that function to induce.
Nov 11, 2014 these observations suggest that the nlrp3/asc/caspase-1 signaling pathway is involved in small ssrna-induced inflammasome activation.
Other inflammasomes are activated by more direct means: double-stranded dna activates the aim2 complex, anthrax toxin activates nlrp1, and bacterial.
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